生物医学工程哲学博士-计算系统与合成生物工程

系统和合成生物工程是相辅相成的新兴领域，结合了实验，计算和理论方法来解决具有挑战性的生物医学问题。系统生物工程基于整合大量分子信息以阐明基因型与表型之间关系的整体方法。对生物系统的这种多尺度理解将有助于回答有关生理系统，人类疾病和治疗策略的重要问题。合成生物工程是从分子生物学组件为有用的目的设计和构建生物学系统。这样的系统具有广泛的复杂生物医学问题的应用。在这些领域中最大的挑战之一是如何获取，操纵和解释海量数据集。该领域的研究还需要对感兴趣的系统有多方面的了解，从分子到细胞再到生物再到生态系统。计算系统和
Systems and synthetic bioengineering are complementary emergent fields that combine experimental, computational and theoretical methods to solve challenging biomedical problems. Systems bioengineering is based on a holistic approach of integrating large amounts of molecular information to elucidate the relationship between genotype and phenotype. This multi-scale understanding of biological systems will help answer important questions about physiological systems, human disease, and therapeutic strategies. Synthetic bioengineering is the design and construction of biological systems from molecular biological components for useful purposes. Such systems have applications in a wide range of complex biomedical problems. Among the greatest challenges in these fields are how to obtain, manipulate, and interpret massive datasets. Research in this area also requires a multi-scale understanding of the system of interest, from molecules to cells to organisms to ecosystems. Computational systems and synthetic bioengineering draw from a wide range of specialties including mathematical modeling, scientific computing, signal processing, molecular biology, and high-throughput technologies to provide a unique approach to solving biomedical problems.