细胞和分子生物学哲学博士-基因组完整性和衰老机理

基因组完整性和衰老机制（GIMA）小组的研究旨在增强我们对与衰老和衰老相关疾病相关的基本，分子和细胞机制的了解。关注的广泛领域包括基因组不稳定和DNA修复，线粒体功能障碍，细胞应激反应，癌症中基因表达失调和糖尿病。在我们的跨学科焦点小组中，实验应用包括各种各样的模型系统，包括转基因和敲除小鼠，哺乳动物细胞培养，发芽酵母酿酒酵母，线虫蠕虫秀丽隐杆线虫和果蝇果蝇。我们的焦点小组与H. Lee Moffitt癌症中心，USF儿科流行病学中心，USF医学院，USF化学，物理和电气工程系，伯德·阿尔茨海默氏症研究所
Research within the Genome Integrity & Mechanisms of Aging (GIMA) group aims to enhance our understanding of fundamental, molecular and cellular mechanisms associated with aging and aging-related diseases. The wide range of areas of interest includes genomic instability and DNA repair, mitochondrial dysfunction, cellular stress response, dysregulation of gene expression in cancer, and diabetes. Experimental applications within our interdisciplinary focus group include a broad array of model systems, including transgenic and knockout mice, mammalian cell culture, the budding yeast Saccharomyces cerevisiae, the nematode worm C. elegans and the fruitfly Drosophila melanogaster. Collaborations with our focus group are found with the H. Lee Moffitt Cancer Center, the USF Pedriatric Epidemiology Center, USF College of Medicine, USF Departments of Chemistry, Physics, and Electrical Engineering, the Byrd Alzheimer's Institute and the USF Center for Drug Discovery and Innovation, as well as research groups at other universities.