细胞与分子生物学哲学博士-结构与计算生物学

结构与计算生物学（SCB）小组的研究重点在于理解生物分子结构和功能的各个方面，并将其应用于基本生物学过程以及疾病机理。SCB的研究人员使用CMMB和USF其他研究支持设施（包括药物发现和创新蛋白质组学中心和NMR设施以及USF计算集群）中提供的最新分析和计算工具。研究领域包括确定固有非结构化蛋白质的结构整体，研究氧化应激诱导的蛋白质修饰的选择性和功能性后果，确定选择性膜转运的基本机制，阐明信号转导机制。分子系统发育学和环境焦磷酸测序。
Research in the Structural and Computational Biology (SCB) group focuses on understanding various aspects of biomolecular structure and function with application to fundamental biological processes as well as mechanisms of disease. SCB investigators use state-of-the art analytical and computational tools available within CMMB and other research support facilities at USF including the Center for Drug Discovery and Innovation Proteomics and NMR facilities and the USF computational cluster. Research areas include determination of structural ensembles of intrinsically unstructured proteins, investigation of the selectivity and functional consequences of oxidative stress-induced protein modifications, determination of mechanisms underlying selective membrane transport, elucidation of signal transduction mechanisms. molecular phylogenetics, and environmental pyrosequencing.