MPhil / PhD / MD细胞与分子生理学

细胞和分子生理学专注于理解分子和细胞过程如何引起复杂的生理功能。我们在现代生理学的各个方面都有专业知识，从基因表达的调控到细胞，组织和整个生物的生物学。我们正在开发协作方式来解决重要的生理问题，为床边的临床医生提供重要的翻译链接。该程序的研究包括分子结构和功能，分子相互作用以及细胞信号传导到复杂细胞表型和通讯的研究，这些信号和通讯是构成高级生物的组织和器官系统整合功能的基础。研究范围从分子，生物物理和计算方法到发育和后基因组生理策略，其模型生物范围从细菌和酵母到果蝇，蠕虫，小鼠和人。哲学硕士（MPhil）
Cellular and Molecular Physiology focuses on understanding how molecular and cellular processes give rise to complex physiologic functions. We have expertise in all aspects of modern physiology, ranging from the regulation of gene expression to cell, tissue and whole organism biology. We have a long and prestigious history and are a leading international centre for research into the fundamental principles of human physiology. We're developing collaborative ways to address important physiological questions, providing vital translational links to clinicians at the bedside.<br><br>Research in this program includes study of molecular structure and function, molecular interactions and cell signalling through to complex cellular phenotypes and communications that underlie the integrated functions of the tissues and organ systems comprising higher living organisms. Research extends from molecular, biophysical and computational methods to developmental and post-genomic physiologic strategies, with model organisms ranging from bacteria and yeast, to fruit-flies, worms, mouse and man.<br><br>We particularly welcome research proposals that match those of our researchers, including:<br><br>Cell physiology, with a focus on intracellular signalling, vesicular transport and the cell cycle<br>Systems physiology, including the cancer microenvironment, gastric physiology, stem cell biology and developmental physiology<br>Smooth muscle physiology, with research in reproductive physiology, ureteric microvessels, respiratory physiology and disease<br>Intestinal epithelial cell biology in health and disease<br>Neuronal signalling, integrating expertise in cell biology, structural biology and the use of model organisms to investigate aging, neurodegeneration and addiction<br>Calcium signalling in health and disease, which is currently focused on the role of Ca2 signalling, mitochondrial function and bioenergetics in pancreatitis and regulated secretion<br>Vascular biology, including the therapeutic use of vascular stents<br>Mechanisms of infection and immune cell response<br>Cancer cell biology, including role of stroma/immune cell microenvironment, cancer cell invasion, migration and metastasis.