Genomics describes the determination of the nucleotide sequence and many further analyses to discover functional and structural information on all the genes of an organism. Topics include the methods and results of functional and structural gene analysis on a genome-wide scale as well as a discussion of the implications of this research. Bioinformatics describes the computational analysis of genomes and macromolecular structures on a large scale. Topics include sequence alignment, biological database design, comparative genomics, geometric analysis of protein structure, and macromolecular simulation. The Yale Computer Science MS offers students the unique opportunity to study with faculty in small classes, and on a one to one basis.Upon acceptance, students may choose to follow the General Track, or may apply to one of the Specialized Tracks in Bioinformatics or in Computing and the Arts. Students in the General Track are advised by the Director of Graduate Studies (DGS). Students in the Specialized Tracks are advised by track faculty, with their final programs subject to approval by the DGS. Students in specialized tracks follow a set of courses that prepare them to do a one term independent project in the area of specialization.The purpose of Specialized Tracks is to allow the student to work more closely with faculty and students in a chosen area and to do an independent project. Choosing or not choosing a specialized track will not affect whether a student is admitted to the MS program. Participation in specialized tracks is not explicitly annotated on the student's diploma or transcript.