分子遗传学理学硕士-分子微生物学和传染病

分子遗传学系由医学大楼管理，有近100名教职员工，其实验室位于医学大楼内
The Department of Molecular Genetics is administered from the Medical Sciences Building and has nearly 100 faculty members whose labs are located within the Medical Science Building, the Best Institute, the Donnelly Centre for Cellular and Biomolecular Research, the FitzGerald Building, the Hospital for Sick Children, Mount Sinai Hospital, the Ontario Institute for Cancer Research, and Princess Margaret Hospital.<br>The Master of Science and Doctor of Philosophy programs in Molecular Genetics offer research training in a broad range of genetic systems from bacteria and viruses to humans. Research projects include DNA repair, recombination and segregation, transcription, RNA splicing and catalysis, regulation of gene expression, signal transduction, interactions of host cells with bacteria and viruses, developmental genetics of simple organisms (worms and fruit flies) as well as complex organisms (mice), molecular neurobiology, molecular immunology, cancer biology and virology, structural biology, and human genetics and gene therapy.<br>MoGen's research in Molecular Microbiology and Infectious Disease tackles fundamental questions about the molecular mechanisms that bacteria, fungi, and viruses employ to achieve their biotic prowess. We aim to understand how pathogens manipulate the host to replicate and cause disease and how the host recognizes, captures, and destroys invading pathogens. We also study basic cellular processes such as genome replication, regulation of gene expression, and responses to stress and environmental cues. This understanding will be critical in enabling us to address global challenges, including developing new strategies to cripple HIV, prevent and treat tuberculosis, halt the spread of sexually transmitted disease, and conquer Legionnaire's Disease, invasive fungal infections, and microbial drug resistance.