博士/硕士药理学

我们的PhD / MPhil药理学计划使您能够进行一项研究项目，以增进对药理学的理解。我们的药理研究集中于一系列主题。这些包括：药物外排转运蛋白的药理学
Our PhD/MPhil Pharmacology programme enables you to undertake a research project that will improve understanding of Pharmacology.<br><br>Our pharmacology research focuses on a range of topics. These include:<br><br>the pharmacology of drug efflux transporters, particularly ABCB1 P-glycoprotein, ABCG2 breast cancer resistance protein and ABCC multidrug resistance-associated transporters,<br>developing complex, physiologically-relevant in vitro cell systems to investigate transport, metabolism and delivery of therapeutic drugs,<br>understanding the pharmacological and molecular mechanisms that regulate expression and function of drug efflux transporters, particularly in the blood-brain barrier,<br>the role of blood-brain barrier drug efflux transporters in drug delivery to the central nervous system and the effects of inflammatory and degenerative conditions, eg Alzheimer's disease, on efflux transporter function,<br>the biological role of lipid networks in health and disease, particularly their roles in inflammation, cellular communications and tissue responses,<br>employing mass spectrometry-based lipidomic technology, in conjunction with functional, metabolic and signaling approaches to characterise lipid profiles in physiological and pathophysiological conditions,<br>investigating the role of lipids in skin homeostasis and in response to inflammation, injury and wound healing,<br>studying role of local hormones in diseases and conditions associated with the female reproductive tract (eg dysmenorrhoea, endometriosis and the detection and prevention of preterm labour),<br>molecularly identifying and pharmacologically characterising receptors expressed in the female reproductive system,<br>understanding the physiological and pharmacological characteristics of the placenta. These studies include the development of placental homing peptide-microRNA inhibitor conjugates for targeted enhancement of placental growth signalling,<br><br>Learn from some of Europe's leading researchers while undertaking your own project.<br>Access some of the best research facilities in the world at both the University and in hospitals around Greater Manchester.<br>Undergo training in transferable skills critical to developing early-stage researchers and professionals through the Doctoral Academy's training programme.<br>Conduct research at a university ranked 6th in the UK (QS World University Rankings 2022).